305 entries « 1 of 7 »
305.

Matos, M J; Vilar, S; Vazquez-Rodriguez, S; Kachler, S; Klotz, K -N; Buccioni, M; Delogu, G; Santana, L; Uriarte, E; Borges, F

Structure-Based Optimization of Coumarin hA<inf>3</inf> Adenosine Receptor Antagonists Journal Article

Journal of Medicinal Chemistry, 63 (5), pp. 2577-2587, 2020, (cited By 1).

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304.

Angona, I P; Daniel, S; Martin, H; Bonet, A; Wnorowski, A; Maj, M; Jóźwiak, K; Silva, T B; Refouvelet, B; Borges, F; Marco-Contelles, J; Ismaili, L

Design, synthesis and biological evaluation of new antioxidant and neuroprotective multitarget directed ligands able to block calcium channels Journal Article

Molecules, 25 (6), 2020, (cited By 0).

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303.

Silva, V; Silva, C; Soares, P; Garrido, E M; Borges, F; Garrido, J

Isothiazolinone biocides: Chemistry, biological, and toxicity profiles Journal Article

Molecules, 25 (4), 2020, (cited By 0).

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302.

Gomes, L R; Low, J N; Borges, F; Gaspar, A; Mesiti, F

The synthesis, crystal structure and Hirshfeld analysis of 4-(3,4-dimethylanilino)-N-(3,4-dimethylphenyl)quinoline-3-carboxamide Gomes Ligia R. Journal Article

Acta Crystallographica Section E: Crystallographic Communications, 76 , pp. 201-207, 2020, (cited By 0).

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301.

Saso, L; Suzen, S; Borges, F; Csont, T

Chemistry and pharmacology of modulators of oxidative stress Journal Article

Current Medicinal Chemistry, 27 (13), pp. 2038-2039, 2020, (cited By 0).

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300.

Benfeito, S; Fernandes, C; Vilar, S; Remião, F; Uriarte, E; Borges, F

Exploring the multi-target performance of mitochondriotropic antioxidants against the pivotal Alzheimer’s disease pathophysiological hallmarks Journal Article

Molecules, 25 (2), 2020, (cited By 0).

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299.

Chavarria, D; Fernandes, C; Silva, V; Silva, C; Gil-Martins, E; Soares, P; Silva, T; Silva, R; Remião, F; Oliveira, P J; Borges, F

Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies Journal Article

European Journal of Medicinal Chemistry, 185 , 2020, (cited By 3).

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298.

Chavarria, D; Fernandes, C; Aguiar, B; Silva, T; Garrido, J; Remião, F; Oliveira, P J; Uriarte, E; Borges, F

Insights into the discovery of novel neuroprotective agents: A comparative study between sulfanylcinnamic acid derivatives and related phenolic analogues Journal Article

Molecules, 24 (23), 2019, (cited By 1).

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297.

Fathalipour, M; Eghtedari, M; Borges, F; Silva, T; Moosavi, F; Firuzi, O; Mirkhani, H

Caffeic Acid Alkyl Amide Derivatives Ameliorate Oxidative Stress and Modulate ERK1/2 and AKT Signaling Pathways in a Rat Model of Diabetic Retinopathy Journal Article

Chemistry and Biodiversity, 16 (12), 2019, (cited By 1).

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296.

Cagide, F; Oliveira, C; Reis, J; Borges, F

Optimizing the synthetic route of chromone-2-carboxylic acids: A step forward to speed-up the discovery of chromone-based multitarget-directed ligands Journal Article

Molecules, 24 (23), 2019, (cited By 1).

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295.

Mesiti, F; Chavarria, D; Gaspar, A; Alcaro, S; Borges, F

The chemistry toolbox of multitarget-directed ligands for Alzheimer's disease Journal Article

European Journal of Medicinal Chemistry, 181 , 2019, (cited By 4).

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294.

Perez-Castillo, Y; Sotomayor-Burneo, S; Jimenes-Vargas, K; Gonzalez-Rodriguez, M; Cruz-Monteagudo, M; Armijos-Jaramillo, V; Cordeiro, M N D S; Borges, F; Sánchez-Rodríguez, A; Tejera, E

CompScore: Boosting Structure-Based Virtual Screening Performance by Incorporating Docking Scoring Function Components into Consensus Scoring Journal Article

Journal of Chemical Information and Modeling, 59 (9), pp. 3655-3666, 2019, (cited By 2).

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293.

Oliveira, C; Bagetta, D; Cagide, F; Teixeira, J; Amorim, R; Silva, T; Garrido, J; Remião, F; Uriarte, E; Oliveira, P J; Alcaro, S; Ortuso, F; Borges, F

Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents Journal Article

European Journal of Medicinal Chemistry, 174 , pp. 116-129, 2019, (cited By 5).

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292.

Malheiro, J F; Maillard, J -Y; Borges, F; Simões, M

Evaluation of cinnamaldehyde and cinnamic acid derivatives in microbial growth control Journal Article

International Biodeterioration and Biodegradation, 141 , pp. 71-78, 2019, (cited By 5).

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291.

Pinto, M; Fernandes, C; Martins, E; Silva, R; Benfeito, S; Cagide, F; Mendes, R F; Paz, Almeida F A; Garrido, J; Remião, F; Borges, F

Boosting drug discovery for parkinson’s: Enhancement of the delivery of a monoamine oxidase-b inhibitor by brain-targeted pegylated polycaprolactone-based nanoparticles Journal Article

Pharmaceutics, 11 (7), 2019, (cited By 0).

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290.

Martins, C; Araújo, F; Gomes, M J; Fernandes, C; Nunes, R; Li, W; Santos, H A; Borges, F; Sarmento, B

Using microfluidic platforms to develop CNS-targeted polymeric nanoparticles for HIV therapy Journal Article

European Journal of Pharmaceutics and Biopharmaceutics, 138 , pp. 111-124, 2019, (cited By 18).

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289.

Chavarria, D; Cagide, F; Pinto, M; Gomes, L R; Low, J N; Borges, F

Development of piperic acid-based monoamine oxidase inhibitors: Synthesis, structural characterization and biological evaluation Journal Article

Journal of Molecular Structure, 1182 , pp. 298-307, 2019, (cited By 2).

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288.

Silva, T; Mohamed, T; Shakeri, A; Rao, P P N; da Silva, Soares P; Remião, F; Borges, F

Repurposing nitrocatechols: 5-Nitro-α-cyanocarboxamide derivatives of caffeic acid and caffeic acid phenethyl ester effectively inhibit aggregation of tau-derived hexapeptide AcPHF6 Journal Article

European Journal of Medicinal Chemistry, 167 , pp. 146-152, 2019, (cited By 7).

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287.

Benfeito, S; Oliveira, C; Fernandes, C; Cagide, F; Teixeira, J; Amorim, R; Garrido, J; Martins, C; Sarmento, B; Silva, R; Remião, F; Uriarte, E; Oliveira, P J; Borges, F

Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction Journal Article

European Journal of Medicinal Chemistry, 167 , pp. 525-545, 2019, (cited By 4).

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286.

Oliveira, I M; Borges, A; Borges, F; Simões, M

Repurposing ibuprofen to control Staphylococcus aureus biofilms Journal Article

European Journal of Medicinal Chemistry, 166 , pp. 197-205, 2019, (cited By 5).

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285.

Pinheiro, S D; Serrão, M P; Silva, T; Borges, F; Soares-da-Silva, P

Pharmacodynamic evaluation of novel Catechol-O-methyltransferase inhibitors Journal Article

European Journal of Pharmacology, 847 , pp. 53-60, 2019, (cited By 1).

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284.

Pacheco, J G; Rebelo, P; Cagide, F; Gonçalves, L M; Borges, F; Rodrigues, J A; Delerue-Matos, C

Electrochemical sensing of the thyroid hormone thyronamine (T<inf>0</inf>AM) via molecular imprinted polymers (MIPs) Journal Article

Talanta, 194 , pp. 689-696, 2019, (cited By 10).

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283.

Malheiro, J F; Maillard, J -Y; Borges, F; Simões, M

Biocide potentiation using cinnamic phytochemicals and derivatives Journal Article

Molecules, 24 (21), 2019, (cited By 1).

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282.

Chavarria, D; Fernandes, C; Silva, T; Garrido, J; Remião, F; Oliveira, P J; Borges, F

Bioisosteric OH- To SH-replacement changes the antioxidant profile of ferulic acid Journal Article

Organic and Biomolecular Chemistry, 17 (44), pp. 9646-9654, 2019, (cited By 1).

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281.

Teixeira, J; Chavarria, D; Borges, F; Wojtczak, L; Wieckowski, M R; Karkucinska-Wieckowska, A; Oliveira, P J

Dietary polyphenols and mitochondrial function: Role in health and disease Journal Article

Current Medicinal Chemistry, 26 (19), pp. 3376-3406, 2019, (cited By 10).

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280.

Gaspar, A; Mohabbati, M; Cagide, F; Razzaghi-Asl, N; Miri, R; Firuzi, O; Borges, F

Searching for new cytotoxic agents based on chromen-4-one and chromane-2,4-dione scaffolds Journal Article

Research in Pharmaceutical Sciences, 14 (1), pp. 74-83, 2019, (cited By 3).

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279.

Caballero-Alfonso, A Y; Cruz-Monteagudo, M; Tejera, E; Benfenati, E; Borges, F; Cordeiro, M N D S; Armijos-Jaramillo, V; Perez-Castillo, Y

Ensemble-based modeling of chemical compounds with antimalarial activity Journal Article

Current Topics in Medicinal Chemistry, 19 (11), pp. 957-969, 2019, (cited By 2).

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278.

Benfeito, S; Oliveira, C; Fernandes, C; Cagide, F; Teixeira, J; Amorim, R; Garrido, J; Martins, C; Sarmento, B; Silva, R; Remiao, F; Uriarte, E; Oliveira, P J; Borges, F

Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction Journal Article

Eur J Med Chem, 167 , pp. 525-545, 2019, ISSN: 1768-3254 (Electronic) 0223-5234 (Linking).

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277.

Gaspar, A; Mohabbati, M; Cagide, F; Razzaghi-Asl, N; Miri, R; Firuzi, O; Borges, F

Searching for new cytotoxic agents based on chromen-4-one and chromane-2,4-dione scaffolds Journal Article

Res Pharm Sci, 14 (1), pp. 74-83, 2019, ISSN: 1735-5362 (Print) 1735-5362 (Linking).

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276.

Oliveira, C; Bagetta, D; Cagide, F; Teixeira, J; Amorim, R; Silva, T; Garrido, J; Remiao, F; Uriarte, E; Oliveira, P J; Alcaro, S; Ortuso, F; Borges, F

Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents Journal Article

Eur J Med Chem, 174 , pp. 116-129, 2019, ISSN: 1768-3254 (Electronic) 0223-5234 (Linking).

BibTeX | Links:

275.

Oliveira, I M; Borges, A; Borges, F; Simoes, M

Repurposing ibuprofen to control Staphylococcus aureus biofilms Journal Article

Eur J Med Chem, 166 , pp. 197-205, 2019, ISSN: 1768-3254 (Electronic) 0223-5234 (Linking).

BibTeX | Links:

274.

Pacheco, J G; Rebelo, P; Cagide, F; Goncalves, L M; Borges, F; Rodrigues, J A; Delerue-Matos, C

Electrochemical sensing of the thyroid hormone thyronamine (T0AM) via molecular imprinted polymers (MIPs) Journal Article

Talanta, 194 , pp. 689-696, 2019, ISSN: 1873-3573 (Electronic) 0039-9140 (Linking).

BibTeX | Links:

273.

Pinheiro, S D; Serrao, M P; Silva, T; Borges, F; Soares-da-Silva, P

Pharmacodynamic evaluation of novel Catechol-O-methyltransferase inhibitors Journal Article

Eur J Pharmacol, 847 , pp. 53-60, 2019, ISSN: 1879-0712 (Electronic) 0014-2999 (Linking).

BibTeX | Links:

272.

Silva, T; Mohamed, T; Shakeri, A; Rao, P P N; da Silva, Soares P; Remiao, F; Borges, F

Repurposing nitrocatechols: 5-Nitro-alpha-cyanocarboxamide derivatives of caffeic acid and caffeic acid phenethyl ester effectively inhibit aggregation of tau-derived hexapeptide AcPHF6 Journal Article

Eur J Med Chem, 167 , pp. 146-152, 2019, ISSN: 1768-3254 (Electronic) 0223-5234 (Linking).

BibTeX | Links:

271.

Hosseini, R; Moosavi, F; Silva, T; Rajaian, H; Hosseini, S Y; Bina, S; Saso, L; Miri, R; Borges, F; Firuzi, O

Modulation of ERK1/2 and Akt pathways involved in the neurotrophic action of caffeic acid alkyl esters Journal Article

Molecules, 23 (12), 2018, (cited By 1).

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270.

Fernandes, C; Martins, C; Fonseca, A; Nunes, R; Matos, M J; Silva, R; Garrido, J; Sarmento, B; Remião, F; Otero-Espinar, F J; Uriarte, E; Borges, F

PEGylated PLGA Nanoparticles As a Smart Carrier to Increase the Cellular Uptake of a Coumarin-Based Monoamine Oxidase B Inhibitor Journal Article

ACS Applied Materials and Interfaces, 10 (46), pp. 39557-39569, 2018, (cited By 12).

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269.

Reis, J; Cagide, F; Valencia, M E; Teixeira, J; Bagetta, D; Pérez, C; Uriarte, E; Oliveira, P J; Ortuso, F; Alcaro, S; Rodríguez-Franco, M I; Borges, F

Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors Journal Article

European Journal of Medicinal Chemistry, 158 , pp. 781-800, 2018, (cited By 16).

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268.

Fernandes, C; Benfeito, S; Amorim, R; Teixeira, J; Oliveira, P J; Remião, F; Borges, F

Desrisking the Cytotoxicity of a Mitochondriotropic Antioxidant Based on Caffeic Acid by a PEGylated Strategy Journal Article

Bioconjugate Chemistry, 29 (8), pp. 2723-2733, 2018, (cited By 4).

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267.

Garrido, E M P J; Cerqueira, A S; Chavarria, D; Silva, T; Borges, F; Garrido, J M P J

Microencapsulation of caffeic acid phenethyl ester and caffeic acid phenethyl amide by inclusion in hydroxypropyl-β-cyclodextrin Journal Article

Food Chemistry, 254 , pp. 260-265, 2018, (cited By 12).

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266.

Ribeiro, J A; Benfeito, S; Cagide, F; Teixeira, J; Oliveira, P J; Borges, F; Silva, A F; Pereira, C M

Electrochemical Behavior of a Mitochondria-Targeted Antioxidant at an Interface between Two Immiscible Electrolyte Solutions: An Alternative Approach to Study Lipophilicity Journal Article

Analytical Chemistry, 90 (13), pp. 7989-7996, 2018, (cited By 2).

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265.

Oliveira, C; Benfeito, S; Fernandes, C; Cagide, F; Silva, T; Borges, F

NO and HNO donors, nitrones, and nitroxides: Past, present, and future Journal Article

Medicinal Research Reviews, 38 (4), pp. 1159-1187, 2018, (cited By 17).

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264.

Reis, J; Cagide, F; Chavarria, D; Silva, T; Fernandes, C; Gaspar, A; Uriarte, E; Remião, F; Alcaro, S; Ortuso, F; Borges, F

Correction to: Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors (Journal of Medicinal Chemistry (2016) 59 (5879-5893) DOI: 10.1021/acs.jmedchem.6b00527) Journal Article

Journal of Medicinal Chemistry, 61 (11), pp. 5054, 2018, (cited By 0).

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263.

Fernandes, C; Pinto, M; Martins, C; Gomes, M J; Sarmento, B; Oliveira, P J; Remião, F; Borges, F

Development of a PEGylated-Based Platform for Efficient Delivery of Dietary Antioxidants Across the Blood-Brain Barrier Journal Article

Bioconjugate Chemistry, 29 (5), pp. 1677-1689, 2018, (cited By 11).

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262.

Reis, J; Manzella, N; Cagide, F; Mialet-Perez, J; Uriarte, E; Parini, A; Borges, F; Binda, C

Tight-Binding Inhibition of Human Monoamine Oxidase B by Chromone Analogs: A Kinetic, Crystallographic, and Biological Analysis Journal Article

Journal of Medicinal Chemistry, 61 (9), pp. 4203-4212, 2018, (cited By 14).

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261.

Teixeira, J; Deus, C M; Borges, F; Oliveira, P J

Mitochondria: Targeting mitochondrial reactive oxygen species with mitochondriotropic polyphenolic-based antioxidants Journal Article

International Journal of Biochemistry and Cell Biology, 97 , pp. 98-103, 2018, (cited By 17).

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260.

Ortuso, F; Bagetta, D; Maruca, A; Talarico, C; Bolognesi, M L; Haider, N; Borges, F; Bryant, S; Langer, T; Senderowitz, H; Alcaro, S

The Mu.Ta.Lig. Chemotheca: A community-populated molecular database for multi-target ligands identification and compound-repurposing Journal Article

Frontiers in Chemistry, 6 (APR), 2018, (cited By 3).

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259.

Oliveira, C; Cagide, F; Teixeira, J; Amorim, R; Sequeira, L; Mesiti, F; Silva, T; Garrido, J; Remião, F; Vilar, S; Uriarte, E; Oliveira, P J; Borges, F

Hydroxybenzoic acid derivatives as dual-target ligands: Mitochondriotropic antioxidants and cholinesterase inhibitors Journal Article

Frontiers in Chemistry, 6 (APR), 2018, (cited By 12).

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258.

Oliveira, C; Gaspar, A; Gomes, L R; Low, J N; Borges, F; Cagide, F

Structural elucidation of a series of benzamide derivatives Journal Article

Magnetic Resonance in Chemistry, 56 (3), pp. 216-223, 2018, (cited By 0).

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257.

Perez-Castillo, Y; Sánchez-Rodríguez, A; Tejera, E; Cruz-Monteagudo, M; Borges, F; Cordeiro, M N D S; Le-Thi-Thu, H; Pham-The, H

A desirability-based multi objective approach for the virtual screening discovery of broad-spectrum anti-gastric cancer agents Journal Article

PLoS ONE, 13 (2), 2018, (cited By 4).

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256.

Teixeira, J; Amorim, R; Santos, K; Soares, P; Datta, S; Cortopassi, G A; Serafim, T L; Sardão, V A; Garrido, J; Borges, F; Oliveira, P J

Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative Journal Article

Toxicology, 393 , pp. 123-139, 2018, (cited By 13).

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305 entries « 1 of 7 »